Tomato-derived extracellular vesicles impact zinc transportation in intestinal epithelial cells
PhD defence, Friday, 29 November 2024, Ziyu Huang
During her PhD studies, Ziyu Huang investigated the health promoting effects of extracellular vesicles isolated from tomatoes. Extracellular vesicles are small, membrane-bound particles that are released by the cells into the extracellular environment. They play a significant role in intercellular communication, transporting various molecules such as proteins, lipids and RNA between cells. Ziyu Huang demonstrated how tomato-derived extracellular vesicles enhanced zinc transportation in intestinal epithelial cells by reducing the levels of metallothionein proteins within these cells.
The new research findings contribute to the understanding of how exogenous extracellular vesicles from edible plants impact the gut of consumers.
The PhD study was completed at Department of Food Science, Faculty of Technical Sciences, Aarhus University.
This summary was prepared by the PhD student.
Time: Friday, 29 November, 2024 at 10:00
Place: Building 5910, room 214, Department of Food Science, Aarhus University, Agro Food Park 48, 8200 Aarhus N
Title of PhD thesis: Impact of plant-based diet on the consumption of health promoting microRNA’s
Contact information: Ziyu Huang, e-mail: ziyuhuang@food.au.dk, tel.: +45 52767735
Members of the assessment committee:
Professor Rachel Errington, Deputy Head School of Medicine, Cardiff University, United Kingdom
Associate Professor Malene Møller Jørgensen, Department of Clinical Medicine, Aalborg University, Denmark
Professor Lotte Bach Larsen (chair), Department of Food Science, Aarhus University, Denmark
Main supervisor:
Associate Professor Martin Krøyer Rasmussen, Department of Food Science, Aarhus University, Denmark
Co-supervisor:
Professor Milena Corredig, Department of Food Science, Aarhus University, Denmark
Language: The PhD dissertation will be defended in English
The defence is public.
The PhD thesis is available for reading at the Graduate School of Technical Sciences/GSTS, Ny Munkegade 120, building 1521, 8000 Aarhus C.