The Future of Diabetes Care: Encapsulation Strategies for Beta Cell Therapy
PhD defence, Thursday 22 February 2024, Mette Steen Toftdal
During her PhD studies, Mette Steen Toftdal explored the encapsulation of beta cells in biomaterials. By transplanting insulin-secreting beta cells into patients with type 1 diabetes, it may be possible to cure the disease entirely. Encapsulation of beta cells into protective biomaterial environments can increase their survival and therapeutic effect. Mette Steen Toftdal studied the survival and function of encapsulated beta cells and improved the biomaterial environment to yield better cell survival.
This research contributes to the ongoing pursuit of finding a cure for type 1 diabetes and offers new avenues for the development of biomaterial-based approaches for diabetes therapy.
The PhD study was completed at Biological and Chemical Engineering, Faculty of Technical Sciences, Aarhus University.
This summary was prepared by the PhD student.
Time: Thursday, 22 February 2024 at 13.00
Place: Building 3130, room 303, Gustav Wieds Vej 10C, 8000 Aarhus C
Title of PhD thesis: Mechanically reinforced beta cell encapsulation device with drug delivery functions.
Contact information: Mette Steen Toftdal, e-mail: firstname.lastname@example.org
Members of the assessment committee:
Professor Junbai Li, Institute of Chemistry, Chinese Academy of Sciences, China
Professor Nils Billestrup, Department of Biomedical Sciences, University of Copenhagen, Denmark
Associate Professor Edzard Spillner (chair), Department of Biological and Chemical Engineering, Aarhus University, Denmark
Associate Professor Menglin Chen, Department of Biological and Chemical Engineering, Aarhus University, Denmark
Lars Groth Grunnet, PhD, Cell Delivery and Formulation, Novo Nordisk A/S, Denmark
Kåre Kryger Vøls, PhD, Cell Delivery and Formulation, Novo Nordisk A/S, Denmark
Camilla Ingvorsen, PhD, In Vivo Cell Efficacy and Histology Novo Nordisk A/S, Denmark
Louise Winkel, PhD, Global Search and Evaluation, Novo Nordisk A/S, Denmark
Language: The PhD dissertation will be defended in English
The defence is public.
The PhD thesis is available for reading at the Graduate School of Technical Sciences/GSTS, Jens Baggesens Vej 53, building 5221, 8200 Aarhus N.