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Engineering of Light-driven Biotransformations

PhD defence, Monday 18 October 2021. Markus Hobisch.

2021.10.18 | Sunitha Satkunam

Markus Hobisch

During his PhD studies, Markus Hobisch investigated the application of light to power biocatalytic reactions in two case studies: The first in organic medium, to maximize substrate loading and therefore productivity and the second at large scale with internal illumination by wireless light emitters (WLEs). Markus Hobisch studied the effect of organic solvents on an enzyme’s stability and increased said stability by entrapping the enzyme in alginate beads, so it was able to operate in pure organic substrate, without any solvent. In the large scale reaction, he optimized reaction conditions and showed that internal illumination by WLEs outperforms traditional illumination methods.

These new research results will contribute to future applications of light-driven enzymatic reactions in organic medium or at large scale, to more efficiently harness the clean energy of light.

The PhD study was completed at the Department for Biological and Chemical Engineering, Faculty of Technical Sciences, Aarhus University.

This summary was prepared by the PhD student.

Time: Monday 18 October 2021 at 13:00
Place: Building 3141, Room 1.08 (Seminarrum 18), Gustav Wieds Vej 10A, 8000 Aarhus C. The PhD defence will also be held online. To receive a link to the event, please send an e-mail to Selin Kara, selin.kara@bce.au.dk 
Title of PhD thesis: Medium and Reaction Engineering of Light-driven Biotransformations
Contact information: Markus Hobisch, e-mail: hobisch@bce.au.dk, tel.: +45 52190956
Members of the assessment committee:
Professor Thomas Scheper, Department of Technical Chemistry, Leibnitz University Hannover, Germany
Professor Willem van Berkel, Department of Agrotechnology and Food Sciences, Wageningen University and Research, Netherlands
Associate Professor Harald Pichler, Institute of Molecular Biotechnology, Graz University of Technology, Austria
Associate Professor Thomas Seviour (chairman), Department of Biological and Chemical Engineering, Aarhus University, Denmark
Main supervisor:
Professor Selin Kara, Department of Biological and Chemical Engineering, Aarhus University, Denmark
Co-supervisor:
Professor Robert Kourist, Institute of Molecular Biotechnology, Graz University of Technology, Austria
Language: The PhD dissertation will be defended in English

The defence is public.

The PhD thesis is available for reading at the Graduate School of Technical Sciences/GSTS,
Katrinebjergvej 89F, building 5132, 8200 Aarhus N.

PhD defence
17427 / i43