Aarhus University Seal

Can gut-modulating foods strengthen your bones?

PhD defence, Friday 2 December 2022, Weiwei He

Weiwei He

During his PhD studies, Weiwei He researched how the introduction of gut-modulating strategies in dairy matrices affects bone mineralization, and if these effects are modulated by gut microbiota activity in an ovariectomized (OVX) rat model, a preferred model for postmenopausal conditions. Increasing evidence shows that the modulation of gut ecosystem has the potential to attenuate bone loss in postmenopausal women. Weiwei He studied how calcium sources, lactose, inulin, milk matrix, and yogurt affects gut-bone associations in OVX rats. In addition, Weiwei He investigated the effects of estrogen-containing drugs (oral contraceptives) in women to understand the associations between estrogen fluctuation and bone metabolism.

The new research findings contribute to the understanding of how the introduction of gut-modulating strategies in dairy matrices affects bone mineralization and how the use of oral contraceptives modulates bone metabolism.

The PhD study was completed at Department of Food Science, Faculty of Technical Sciences, Aarhus University.

This summary was prepared by the PhD student.

Time: Friday, 2 December 2022 at 10 am
Place: Building 5910, room 214, Department of Food Science, Aarhus University, Agro Food Park 48, 8200 Aarhus N
Title of PhD thesis: Enhancing bone mineralization by the introduction of gut-modulating strategies in dairy matrices

Contact information: Weiwei He, e-mail: weiweihe@food.au.dk, tel.: +45 50327925

Members of the assessment committee:

Professor Thom Hubbertz, Department of Agrotechnology and Food Sciences, Wageningen University & Research, Netherlands

Associate professor Henrik Munch Roager, Department of Nutrition, Exercise and Sports, University of Copenhagen, Denmark

Associate professor Marianne Hammershøj (chair), Department of Food Science, Aarhus University, Denmark

Main supervisor:
Professor Hanne Christine Bertram, Department of Food Science, Aarhus University, Denmark

Co-supervisors:

Adj. Professor Henrik Jørgen Andersen, Arla Foods amba, Aarhus, Denmark

Post-doc Rebekka Thøgersen, Department of Food Science, Aarhus University, Denmark

Language: The PhD dissertation will be defended in English

The defence is public.
The PhD thesis is available for reading at the Graduate School of Technical Sciences/GSTS,

Jens Baggesens Vej 53, building 5221, 8200 Aarhus N.

 

17427 / i43