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A good start in life is crucial for success – Inoculation of probiotics to newborn piglets is a promising strategy ensuring robustness at weaning

PhD defence, Friday 25 June 2021, Lea Hübertz Birch Hansen

2021.06.25 | Helle Mitzi Thomsen Reichl

Lea Hübertz Birch Hansen

During her PhD studies, Lea Hübertz Birch Hansen carried out a functional in vitro screening allowing to select probiotic strains intended for an early inoculation product to piglets. The selected multi-species probiotic was evaluated in a proof of concept in vivo study with the aim of understanding the impact of early probiotic priming on the gut microbiota and immune responses. Lea Hübertz Birch Hansen also investigated whether early probiotic inoculation increases the robustness of piglets by conducting an E. coli challenge post-weaning.

The new research findings contribute to understanding the mechanisms involved in probiotic inoculation of newborn piglets, and provide insight into the effect after cessation of probiotic administration and the dynamics during post-weaning diarrhea.

The PhD study was an Industrial PhD project in cooperation with the Department of Animal Science, Faculty of Technical Sciences, Aarhus University and Chr. Hansen A/S, Animal Health Innovation.

This summary was prepared by the PhD student.

Time: Friday, 25 June 2021 at 14:00
Place: Building 8814, room 3050, M2, Department of Animal Science, Aarhus University, Blichers Alle 20, 8830 Tjele
To receive a link to the event, please send an e-mail to Charlotte Steffensen; charlotte.steffensen@anis.au.dk.
Title of PhD thesis: RobustPig – Early inoculation of probiotics to newborn piglets

Contact information: Lea Hübertz Birch Hansen, e-mail: dkleha@chr-hansen.com, tel.: +45 22495109

Members of the assessment committee:

Professor and Associate Director Andrew Van Kessel, Department of Animal and Poultry Science and Vaccine and Infectious Disease Organization, University of Saskatchewan, Canada

Professor Jerry Wells, Department of Animal Sciences, Host-Microbe Interactomics, Wageningen University and Research, Holland, and Department of Veterinary Medicine, University of Cambridge, England.

Senior scientist Ole Højberg (chairman), Department of Animal Science, Aarhus University, Denmark

University supervisors:

Senior Scientist Nuria Canibe, Department of Animal Science, Aarhus University, Denmark

Professor Charlotte Lauridsen, Department of Animal Science, Aarhus University, Denmark

Company supervisors:
Director of Innovation, Bea Nielsen, Chr. Hansen A/S Animal Health Innovation, Denmark

Scientific Affairs Senior Manager, Lisbeth Jørgensen, Chr. Hansen A/S Commercial Development, Denmark

Language: The PhD dissertation will be defended in English

The defence is public.
Due to the coronavirus situation, the PhD thesis will not be available for reading at the offices of the PhD administration. Instead, interested parties may send an e-mail to gradschool.tech@au.dk to receive a digital copy of the PhD thesis. Please note, it may in certain cases be necessary to make an individual arrangement to read the PhD thesis.

PhD defence
17427 / i43